Faculty of Health Sciences
Danielle Badro
Assistant Professor - Graduate Program Coordinator
Office: Block A, Room 402
Campus: Ashrafieh
Extension: 245

Dr. Danielle Badro earned a B.S. in Biology from Saint Joseph University (USJ) in Beirut in 2002 and a Master’s degree in Developmental Biology/Embryology from Université de la Méditerranée (Aix-Marseille 2) in 2004. During that time, she was trained in La Timone Hospital in Marseille, under the supervision of Pr. Michel Fontes. She used the newly discovered at the time recombination techniques to genetically modify the murine Polycystic Kidney Disease 1 gene and produce humanized mutant mice. In May 2009, Dr. Badro obtained a Ph.D. in Molecular and Cell Biology from the Université de Nice-Sophia Antipolis under Dr. Andreas Schedl’s supervision. Her research work included the production of transgenic animals, ex vivo cultures, and microarray analyses studying the role of signaling pathways in the control of cell survival in the embryonic kidney.

After completing her Ph.D., Dr. Badro was appointed as a post-doc fellow at the Lebanese American University in Beirut and later as a post-doc in Molecular Cancerology at the Faculty of Medicine at the American University of Beirut. In 2015, she became a full-time Assistant Professor of Biology and Graduate Program Coordinator in the Faculty of Health Sciences at AUST. She is an academic lecturer and researcher and is currently addressing tumorigenic events in human immortalized and transformed cells, using in vitro strategies and knockdown approaches. She was recently co-awarded a grant by the Lebanese CNRS to investigate the use of nanoparticles in the treatment of aggressive types of metastatic breast cancers. Her other research interests include public health studies related to pharmacy practice and drug consumption.

Over the past ten years, Dr Badro has been a board and committee member for several NGOs supporting cancer children being treated in Lebanon. She is an outdoor enthusiast and summited Mount Kilimanjaro in September 2016 (#UP382150) and completed the GR20 180km-trail in Corsica in June 2018 to raise funds for cancer patients’ treatments and to raise awareness about the importance of early detection in cancer.

Selected Publications

  • Harajly M, Zalzali H, Nawaz Z, Ghayad SE, Ghamloush F, Basma H, Zainedin S, Rabeh W, Jabbour M, Tawil A, Badro DA, Evan GI, Saab R. p53 Restoration in Induction and Maintenance of Senescence: Differential Effects in Premalignant and Malignant Tumor Cells. Mol Cell Biol. 2015 Nov 23;36(3):438-51. doi: 10.1128/MCB.00747-15.
  • Motamedi FJ*,  Badro DA*, Clarkson M*, Lecca MR, Bradford ST, Buske FA, Saar K, Hübner N, Brändli AW, Schedl A. WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors. Nat Commun. 2014 Jul 17;5:4444. doi: 10.1038/ncomms5444.
  • Badro DA, Douaihy B, Haber M, Youhanna SC, Salloum A, Ghassibe-Sabbagh M, Johnsrud B, Khazen G, Matisoo-Smith E, Soria-Hernanz DF, Wells RS, Tyler-Smith C, Platt DE, Zalloua PA; Genographic Consortium. Y-chromosome and mtDNA genetics reveal significant contrasts in affinities of modern Middle Eastern populations with European and African populations. PLoS One. 2013;8(1):e54616. doi: 10.1371/journal.pone.0054616. Epub 2013 Jan 30.
  • Grandjean V, Badro DA, Kiani J. RNA: a possible contributor to the 'missing heritability'. Basic Clin Androl. 2013 Nov 1;23:9. doi: 10.1186/2051-4190-23-9. eCollection 2013.
  • Ghassibe-Sabbagh M, Platt DE, Youhanna S, Abchee AB, Stewart K, Badro DA, Haber M, Salloum AK, Douaihy B, el Bayeh H, Othman R, Shasha N, Kibbani S, Chammas E, Milane A, Nemr R, Kamatani Y, Hager J, Cazier JB, Gauguier D, Zalloua PA; FGENTCARD Consortium. Genetic and environmental influences on total plasma homocysteine and its role in coronary artery disease risk. Atherosclerosis. 2012 May;222(1):180-6. doi: 10.1016/j.atherosclerosis.2012.02.035. Epub 2012 Feb 28.
  • Saade S, Cazier JB, Ghassibe-Sabbagh M, Youhanna S, Badro DA, Kamatani Y, Hager J, Yeretzian JS, El-Khazen G, Haber M, Salloum AK, Douaihy B, Othman R, Shasha N, Kabbani S, Bayeh HE, Chammas E, Farrall M, Gauguier D, Platt DE, Zalloua PA; FGENTCARD consortium. Large scale association analysis identifies three susceptibility loci for coronary artery disease. PLoS One. 2011;6(12):e29427. doi: 10.1371/journal.pone.0029427. Epub 2011 Dec 27.
  • Haber M, Platt DE, Badro DA, Xue Y, El-Sibai M, Bonab MA, Youhanna SC, Saade S, Soria-Hernanz DF, Royyuru A, Wells RS, Tyler-Smith C, Zalloua PA; Genographic Consortium. Influences of history, geography, and religion on genetic structure: the Maronites in Lebanon. Eur J Hum Genet. 2011 Mar;19(3):334-40. doi: 10.1038/ejhg.2010.177. Epub 2010 Dec 1.
  • Haber M, Platt DE, Khoury S, Badro DA, Abboud M, Tyler-Smith C, Zalloua PA. Y-chromosome R-M343 African lineages and sickle cell disease reveal structured assimilation in Lebanon. J Hum Genet. 2011 Jan;56(1):29-33. doi: 10.1038/jhg.2010.131. Epub 2010 Oct 28.

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